Mutations in the SARS-CoV-2 spike proteins affected the ACE2-binding affinity during the development of Omicron pandemic variants
Kouichi Tachibana, Yoshihiko Nakamura, Thi Ly, Takanori Kihara, Hiroshi Kawada, Norio Yamamoto, Kiyoshi Ando
Topics & Concepts
Strain (injury)ChemistryMutationMolecular biologyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)PhenotypeBinding siteWild typeBiologyBiophysicsGeneMutantBiochemistryMedicinePathologyInfectious disease (medical specialty)AnatomyDiseaseSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesCRISPR and Genetic Engineering