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Inhibition of thioredoxin reductase by natural anticancer candidate β-lapachone accounts for triggering redox activation-mediated HL-60 cell apoptosis

Junmin Zhang, Qianhe Xu, Di Ma

2022Free Radical Biology and Medicine21 citationsDOI

Topics & Concepts

Thioredoxin reductaseThioredoxinCancer cellChemistryApoptosisCytotoxicityCell biologyBiochemistryEnzymeBiologyCancerIn vitroGeneticsBioactive Compounds and Antitumor AgentsSynthesis and biological activitySynthesis and Biological Evaluation
Inhibition of thioredoxin reductase by natural anticancer candidate β-lapachone accounts for triggering redox activation-mediated HL-60 cell apoptosis | Litcius