Construction of a nanotheranostic system Zr-MOF@PPa/AF@PEG for improved photodynamic therapy effects based on the PDT‑oxygen consumption and hypoxia sensitive chemotherapeutic drug
Xingchao Wang, Zhiqiang Wang, Wei Ma, Xiaodan Wu, Wen Fang, Changhong Guo, Yingxue Jin
Topics & Concepts
Photodynamic therapyPhotosensitizerIn vivoTumor microenvironmentChemistryCancer researchHypoxia (environmental)Tumor hypoxiaReactive oxygen speciesBiocompatibilityDrug deliveryDrugOxygenPharmacologyBiophysicsBiochemistryPhotochemistryMedicineRadiation therapyTumor cellsSurgeryOrganic chemistryBiologyBiotechnologyNanoplatforms for cancer theranosticsCancer, Hypoxia, and MetabolismMetal-Organic Frameworks: Synthesis and Applications