Two long-lasting human monoclonal antibodies cross-react with monkeypox virus A35 antigen
Bing Zhou, Haiyan Wang, Lin Cheng, Chengyan Zhao, Xinrong Zhou, Xuejiao Liao, Xiangyang Ge, Lei Liu, Xiaobo Lu, Bin Ju, Zheng Zhang
Abstract
Human monkeypox has been a rare zoonotic disease caused by the monkeypox virus (MPXV) infection which is mainly reported in West and Central Africa in the past 1 . However, since the first confirmed case was found in the United Kingdom on May 7, 2022, there were over 87,000 confirmed cases worldwide until April, 2023 ( https://worldhealthorg.shinyapps.io/mpx_global/ ). Human monkeypox seems to have become a multi-country outbreak disease and it was declared a Public Health Emergency of International Concern by the World Health Organization on July 23, 2022.
Topics & Concepts
VirologyMonkeypoxMonoclonal antibodyAntigenAntibodyVirusChemistryBiologyImmunologyRecombinant DNAGeneBiochemistryVacciniaPoxvirus research and outbreaksHerpesvirus Infections and TreatmentsBacillus and Francisella bacterial research