Glyoxal Induces Senescence in Human Keratinocytes through Oxidative Stress and Activation of the Protein Kinase B/FOXO3a/p27KIP1 Pathway
Rym Halkoum, Virginie Salnot, C. Capallere, C. Plaza, Aurore L’honoré, Karl Pays, Bertrand Friguet, Carine Nizard, Isabelle Petropoulos
Topics & Concepts
SenescenceCell biologyGlycationMethylglyoxalPhenotypeOxidative stressBiologySecretionBiochemistryGeneReceptorEnzymeAdvanced Glycation End Products researchTelomeres, Telomerase, and SenescenceSkin Protection and Aging