Electronic Mapping of a Bacterial Genome with Dual Solid-State Nanopores and Active Single-Molecule Control
Arthur Rand, Philip Zimny, Roland Nagel, Chaitra Telang, Justin Mollison, Aaron S. Bruns, Emily Leff, Walter Reisner, William B. Dunbar
Abstract
genome. With an appropriately designed array, higher throughput implementations could enable human-sized genome and epigenome mapping applications.
Topics & Concepts
GenomeNanoporeDNANanopore sequencingEpigenomeComputational biologyEscherichia coliDNA sequencingNanotechnologyComputer scienceBiologyMaterials scienceGeneticsGeneGene expressionDNA methylationNanopore and Nanochannel Transport StudiesAdvanced biosensing and bioanalysis techniquesBacteriophages and microbial interactions