Synthesis and structure activity relationship of the first class of LXR inverse agonists
Bahaa Elgendy, Kristine Griffett, Lamees Hegazy, Paolo Di Fruscia, Kirby R. Sample, Emmalie Schoepke, Theodore M. Kamenecka, Thomas P. Burris
Topics & Concepts
Liver X receptorInverse agonistChemistryGene isoformNuclear receptorPharmacologyAgonistReceptorBiochemistryGeneComputational biologyBiologyTranscription factorCholesterol and Lipid MetabolismDrug Transport and Resistance MechanismsPeroxisome Proliferator-Activated Receptors