A nanoparticle probe for the imaging of autophagic flux in live mice via magnetic resonance and near-infrared fluorescence
Howard H. Chen, Zehedina Khatun, Wei Lan, Choukri Mekkaoui, Dakshesh Patel, Sally Ji Who Kim, Asma Boukhalfa, Efosa Enoma, Meng Lin, Yinching I. Chen, Leena Kaikkonen, Guoping Li, Diane E. Capen, Parul Sahu, Anand T. N. Kumar, Robert M. Blanton, Hushan Yuan, Saumya Das, Lee Josephson, David E. Sosnovik
Topics & Concepts
AutophagyBafilomycinCathepsin DChemistryBiophysicsCell biologyNanoprobeNanoparticleFluorescence-lifetime imaging microscopyPhagosomeFlux (metallurgy)Fluorescence microscopeFluorescenceMaterials scienceBiochemistryNanotechnologyBiologyApoptosisEnzymeQuantum mechanicsOrganic chemistryIntracellularPhysicsAutophagy in Disease and TherapyCalcium signaling and nucleotide metabolismAdenosine and Purinergic Signaling