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Hypermetabolic Cerebellar Connectome in Alzheimer's Disease

Vinay Gupta, Samuel Booth, Ji Hyun Ko, for the Alzheimer's Disease Neuroimaging Initiative

2021Brain Connectivity17 citationsDOIOpen Access PDF

Abstract

Introduction: Regional hypermetabolism in Alzheimer's disease (AD), especially in the cerebellum, has been consistently observed but often neglected as an artefact produced by the commonly used proportional scaling procedure in the statistical parametric mapping. We hypothesize that the hypermetabolic regions are also important in disease pathology in AD.

Topics & Concepts

ConnectomeNeuroscienceFunctional connectivityCerebellumAlzheimer's diseaseResting state fMRIPsychologyDiseaseMedicinePathologyFunctional Brain Connectivity StudiesAdvanced Neuroimaging Techniques and ApplicationsAdvanced MRI Techniques and Applications
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