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Icariin inhibits RANKL-induced osteoclastogenesis in RAW264.7 cells via inhibition of reactive oxygen species production by reducing the expression of NOX1 and NOX4

Ruifeng Ji, Dou Wu, Qiang Liu

2022Biochemical and Biophysical Research Communications16 citationsDOI

Topics & Concepts

RANKLIcariinChemistryNicotinamide adenine dinucleotide phosphateReactive oxygen speciesOsteoclastNOX4Tartrate-resistant acid phosphataseApocyninNADPH oxidaseCell biologyActivator (genetics)PharmacologyBiochemistryCancer researchReceptorOxidase testBiologyEnzymeMedicinePathologyAlternative medicineBone Metabolism and DiseasesMedicinal Plant Pharmacodynamics ResearchCytokine Signaling Pathways and Interactions
Icariin inhibits RANKL-induced osteoclastogenesis in RAW264.7 cells via inhibition of reactive oxygen species production by reducing the expression of NOX1 and NOX4 | Litcius