pH and redox dual-sensitive drug delivery system constructed based on fluorescent carbon dots
Boye Zhang, Qianqian Duan, Yi Li, Jianming Wang, Wendong Zhang, Shengbo Sang
Abstract
circulation and tumor targeting. Notably, the cytotoxicity of the drug delivery system on cancer cells was comparable to that of cisplatin, while the side effects on normal cells were significantly reduced. In addition, the system realized recognition of cancer cells by the high-contrast fluorescent imaging. In conclusion, the CDs-Pt(iv)-PEG system provided a promising potential for effective delivery of anticancer drugs and cancer cells screening.
Topics & Concepts
FluorescenceDrug deliveryRedoxDual (grammatical number)ChemistryNanotechnologyCarbon fibersDrugCombinatorial chemistryMaterials sciencePharmacologyInorganic chemistryMedicinePhysicsComposite materialComposite numberLiteratureQuantum mechanicsArtCarbon and Quantum Dots ApplicationsAdvanced Nanomaterials in CatalysisGraphene and Nanomaterials Applications