Robust and Tumor-Environment-Activated DNA Cross-Linker Driving Nanoparticle Accumulation for Enhanced Therapeutics
Zhicong Chao, Hongwei Lu, Fan Xiao, Chen Shao, Zixiang Wei, Jiantao Yu, Xindan Zhang, Li Lin, Leilei Tian
Abstract
Agglomeration of therapeutic nanoparticles in response to tumor microenvironments is a promising approach to enhance drug accumulation and improve therapeutic efficacy. Cytosine-rich DNA sequences ...
Topics & Concepts
LinkerNanoparticleDNANanotechnologyChemistryBiophysicsCell biologyMaterials scienceComputer scienceBiochemistryBiologyOperating systemAdvanced biosensing and bioanalysis techniquesRNA Interference and Gene DeliveryGold and Silver Nanoparticles Synthesis and Applications