d-mannose targets PD-1 to lysosomal degradation and enhances T cell-mediated anti-tumor immunity
Wenjing Dong, Mingen Lin, Ruonan Zhang, Xue Sun, Hongchen Li, Tianshu Liu, Yanping Xu, Lei Lv
Topics & Concepts
MannoseImmunityDegradation (telecommunications)Immune systemChemistryCellular immunityCancer researchCell biologyBiologyImmunologyBiochemistryComputer scienceTelecommunicationsImmune Cell Function and InteractionCytomegalovirus and herpesvirus researchAdenosine and Purinergic Signaling