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Coinfection of COVID-19 and Tuberculosis in Uganda

Edwin Nuwagira, Stellah Mpagama, Asumpta Katusiime, Bobson Natamba, Joseph Baruch Baluku, Peggy S. Lai

2023American Journal of Tropical Medicine and Hygiene10 citationsDOIOpen Access PDF

Abstract

The clinical features and outcomes of tuberculosis (TB) and COVID-19 coinfection are not well established. This short report describes 11 people with TB/COVID-19 coinfection in Uganda. The mean age was 46.9 ± 14.5 years; eight (72.7%) were male and two (18.2%) were coinfected with HIV. All patients presented with cough whose median duration was 71.1 (interquartile range, 33.1, 109) days. Eight (72.7%) had mild COVID-19 whereas two (18.2%) died, including one with advanced HIV disease. All patients were treated with first-line anti-TB drugs and adjunct therapy for COVID-19 using national treatment guidelines. This report presents the possibility of the coexistence of the two diseases and calls for more vigilance, screening, and collective prevention measures for both COVID-19 and TB.

Topics & Concepts

CoinfectionTuberculosisMedicineInterquartile rangeCoronavirus disease 2019 (COVID-19)Internal medicineHuman immunodeficiency virus (HIV)DiseaseVirologyInfectious disease (medical specialty)PathologyTuberculosis Research and EpidemiologyCOVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research
Coinfection of COVID-19 and Tuberculosis in Uganda | Litcius