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EPIDEMIOLOGY AND ANTIBIOTIC RESISTANCE PROFILE OF BACTERIAL UROPATHOGENS IN MALE PATIENTS: A 10-YEAR RETROSPECTIVE STUDY

Márió Gajdács

2021FARMACIA16 citationsDOIOpen Access PDF

Abstract

The purpose of our present study was to establish the incidence of UTIs in adult male patients in the Southern region of Hungary over a long surveillance period (2008 -2017). The antimicrobial susceptibility testing was performed using the disk diffusion method. Overall, n = 3750 of these outpatient samples (17.73%) and n = 5902 of inpatient samples (30.54%) originated from male patients. Members of the Enterobacteriaceae family were the most commonly isolated (outpatient: 64.4%, inpatient: 55.57%), with E. coli being the most common urinary pathogen in male patients (outpatient: 37.23%, inpatient: 27.40%), followed by Enterococcus spp. (outpatient: 22.72%, inpatient: 23.43%), and P. aeruginosa (outpatient: 7.15%, inpatient: 9.2%). Between 2010 and 2017, n = 501 (62.65 13.51 per year) extended-spectrum -lactamase (ESBL) -positive isolates were recorded from outpatients and n = 737 (105.28 31.99 per year) from inpatients (p = 0.032). Similarly to other bacterial infections, patients affected by drug-resistant urinary pathogens may encounter a poor clinical outcome and complications.

Topics & Concepts

EpidemiologyMedicineAntibiotic resistanceAntibioticsRetrospective cohort studyResistance (ecology)MicrobiologyInternal medicineBiologyEcologyUrinary Tract Infections ManagementUrinary Bladder and Prostate ResearchPelvic floor disorders treatments