Electrochemical reductive cross-coupling of acyl chlorides and sulfinic acids towards the synthesis of thioesters
Jie Xu, Fangling Lu, Linghong Sun, Mingna Huang, Jianwei Jiang, Ke Wang, Dandan Ouyang, Lijun Lu, Aiwen Lei
Abstract
In this context, we used an electrochemical reduction method to obtain thiyl radicals from sulfinic acids. In a simple undivided cell, various acyl chlorides and sulfinic acids were compatible, generating 40 examples of the desired thioesters.
Topics & Concepts
Sulfinic acidChemistryContext (archaeology)ElectrochemistryCombinatorial chemistryOrganic chemistryBiologyElectrodePaleontologyPhysical chemistrySulfur-Based Synthesis TechniquesRadical Photochemical ReactionsCatalytic C–H Functionalization Methods