Litcius/Paper detail

Natural killer cells for antiviral therapy

Davey M. Smith, Jolie Schafer, Brian P. Tullius, Laura Witkam, Silke Paust

2023Science Translational Medicine17 citationsDOI

Abstract

Natural killer (NK) cell-based immunotherapy is being explored for treating infectious diseases, including viral infections. Here, we discuss evidence of NK cell responses to different viruses, ongoing clinical efforts to treat such infections with NK cell products, and review platforms to generate NK cell products.

Topics & Concepts

ImmunotherapyImmunologyNatural killer cellCellMedicineVirologyBiologyImmune systemCytotoxicityBiochemistryGeneticsIn vitroImmune Cell Function and InteractionCAR-T cell therapy researchAutoimmune and Inflammatory Disorders Research