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Molecular characterization of the human kidney interstitium in health and disease

Daria Barwinska, Tarek M. El‐Achkar, Ricardo Melo Ferreira, Farooq Syed, Ying‐Hua Cheng, Seth Winfree, Michael J. Ferkowicz, Takashi Hato, Kimberly S. Collins, Kenneth W. Dunn, Katherine J. Kelly, Timothy A. Sutton, Brad H. Rovin, Samir V. Parikh, Carrie L. Phillips, Pierre C. Dagher, Michael T. Eadon, for the Kidney Precision Medicine Project

2021Science Advances46 citationsDOIOpen Access PDF

Abstract

) were identified. LMD transcriptomics complements snRNAseq; together, they facilitate mapping of interstitial marker genes to aid interpretation of pathophysiology in precision medicine studies.

Topics & Concepts

Laser capture microdissectionMicrodissectionComputational biologyIn situ hybridizationKidneyBiologyKidney diseasePathologyGeneMedicineGeneticsGene expressionEndocrinologyRenal and related cancersRenal cell carcinoma treatmentTissue Engineering and Regenerative Medicine
Molecular characterization of the human kidney interstitium in health and disease | Litcius