Cooperative palladium-catalyzed P(NEt<sub>2</sub>)<sub>3</sub>-mediated (4 + 1) annulation of isatins with 2 hydroxymethylallylcarbonates
Zhipeng Zhang, Li Jing, Er‐Qing Li, Zheng Duan
Abstract
Cooperative palladium-catalyzed and P(NEt 2 ) 3 -mediated (4 + 1) annulations are developed, leading to a big library of spirooxindole derivatives in high structural diversity.
Topics & Concepts
ChemistryAnnulationPalladiumCatalysisCombinatorial chemistryMedicinal chemistryOrganic chemistryCatalytic C–H Functionalization MethodsSynthetic Organic Chemistry MethodsAsymmetric Synthesis and Catalysis