Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency
Blake A. Caldwell, Monica Yun Liu, Rexxi D. Prasasya, Tong Wang, Jamie E. DeNizio, N. Adrian Leu, Nana Yaa A. Amoh, Christopher Krapp, Yemin Lan, Emily Shields, Roberto Bonasio, Christopher J. Lengner, Rahul M. Kohli, Marisa S. Bartolomei
Topics & Concepts
ReprogrammingDNA demethylation5-HydroxymethylcytosineBiologySomatic cellChromatinEpigeneticsDemethylationCell biologyDNADNA methylation5-MethylcytosineEpigenesisEmbryonic stem cellGeneticsCellGeneGene expressionEpigenetics and DNA MethylationGenetics and Neurodevelopmental DisordersPluripotent Stem Cells Research