Perilipin 5 ameliorates high-glucose-induced podocyte injury via Akt/GSK-3β/Nrf2-mediated suppression of apoptosis, oxidative stress, and inflammation
Jie Feng, Liyi Xie, Xiaoyang Yu, Chao Liu, Hongjuan Dong, Wanhong Lu, Ranran Kong
Topics & Concepts
PodocyteEndocrinologyOxidative stressChemistryInternal medicineProtein kinase BPerilipinGSK-3InflammationDownregulation and upregulationApoptosisCell biologySignal transductionBiologyMedicineBiochemistryKidneyAdipocyteGeneProteinuriaAdipose tissueLipid metabolism and biosynthesisPlant pathogens and resistance mechanismsGenomics, phytochemicals, and oxidative stress