Mangiferin and Taurine Ameliorate MSRV Infection by Suppressing NF-κB Signaling
Caijiao Dai, Li Yu, Zhiwen Wang, Peng Deng, Lijuan Li, Zemao Gu, Xugang He, Jianghua Wang, Junfa Yuan
Abstract
rhabdovirus (MSRV) and revealed its pathophysiology of inflammation and oxidative stress. Aiming to dampen and redirect inflammatory responses, mangiferin or taurine exhibited their antiviral capability by suppressing NF-κB signaling. Our findings exemplify a practice approach to develop broad-spectrum antivirals by dampening and redirecting inflammatory responses.
Topics & Concepts
Proinflammatory cytokineOxidative stressBiologyReactive oxygen speciesInflammationMangiferinTumor necrosis factor alphaTranscriptomePharmacologyImmunologyBiochemistryGene expressionGeneAquaculture disease management and microbiotaImmune Cell Function and InteractionMangiferin and Mango Extracts