Cu-catalysed Chan–Evans–Lam reaction meets deep eutectic solvents: efficient and selective C–N bond formation under aerobic conditions at room temperature
Luciana Cicco, Paola Vitale, Filippo Maria Perna, Vito Capriati, Joaquín García‐Álvarez
Abstract
The Cu( ii )-catalysed Chan–Evans–Lam amination between organoboron compounds and primary amines can be conducted and scaled up in Deep Eutectic Solvents as recyclable and sustainable reaction media, and in the absence of external ligands.
Topics & Concepts
Eutectic systemAminationChemistryDeep eutectic solventOrganic chemistryMedicinal chemistryPolymer chemistryCatalysisAlloyCatalytic Cross-Coupling ReactionsCatalytic C–H Functionalization MethodsAsymmetric Hydrogenation and Catalysis