Regulating Neutrophil PAD4/NOX-Dependent Cerebrovasular Thromboinflammation
Junaid Ansari, Shantel Vital, Shreya Yadav, Felicity N. E. Gavins
Abstract
neutrophils, which may further explain attenuation of cerebral thrombosis. Overall, this study presents a viable pre-clinical model of prevention and management of thromboinflammatory complications such as ischemic stroke.
Topics & Concepts
Neutrophil extracellular trapsImmunologyNOxIn vivoNADPH oxidaseMicrocirculationMedicineInflammationReactive oxygen speciesChemistryBiologyBiochemistryInternal medicineBiotechnologyCombustionOrganic chemistryNeutrophil, Myeloperoxidase and Oxidative MechanismsAtherosclerosis and Cardiovascular DiseasesAcute Ischemic Stroke Management