Photochemical Selective Oxidation of Benzyl Alcohols to Aldehydes or Ketones
Zhenxiang He, Bo Yin, Xiaohuan Li, Xian‐Li Zhou, Hai-Ning Song, Jin‐Bu Xu, Feng Gao
Abstract
as an oxidant, the present study reports a new photochemical protocol that enables efficient aerobic oxidation of various benzyl alcohols to the corresponding aldehydes or ketones in excellent yields under mild reaction conditions. The catalyst system presents good functional-group tolerance and exquisite chemoselectivity, which also can easily be scaled-up to gram scale. Moreover, the methodological applications in practical synthesis of several organic molecules and the primary reaction mechanism were also discussed.
Topics & Concepts
ChemoselectivityChemistryFunctional groupEosin YCatalysisPhotochemistryPhotocatalysisAlcohol oxidationAldehydeCombinatorial chemistryOrganic chemistryPolymerOxidative Organic Chemistry ReactionsRadical Photochemical ReactionsChemical Synthesis and Reactions