Bismuth dithiocarbamate complexes as anticancer agents and beyond: a comprehensive review
Deepika Verma, Kiran Gupta, Snober S. Mir, Om Prakash
Abstract
studies reveal that bismuth dithiocarbamates (Bi-DTC) can effectively induce apoptosis, suppress tumour growth, and overcome chemoresistance, positioning them as innovative therapeutic options. This review examines the synthesis strategies, biological mechanisms, and experimental evidence supporting the anticancer potential of these complexes. It also highlights their antimicrobial and antileishmanial activities, emphasising the role of antimicrobial properties in preventive and supportive therapies during cancer treatment. However, further investigations are essential to delineate their mechanisms of action and optimise their clinical applicability for cancer treatment.
Topics & Concepts
DithiocarbamateBismuthChemistryAnticancer drugCombinatorial chemistryNanotechnologyPharmacologyMaterials scienceDrugOrganic chemistryMedicineOrganometallic Compounds Synthesis and CharacterizationSynthesis and biological activityMetal complexes synthesis and properties