B cells polarize pathogenic inflammatory T helper subsets through ICOSL-dependent glycolysis
Qiu‐Hui Zeng, Wei Yuan, Xiang‐Ming Lao, Dong‐Ping Chen, Chun-Xiang Huang, Qianyi Lin, Min He, Yuan Liao, Limin Zheng, Bo Li, Guangbo Zhang, Yun Chen, Dong‐Ming Kuang
Abstract
B cells have a previously unrecognized helper function in triggering pathogenic differentiation of inflammatory T H subsets.
Topics & Concepts
Function (biology)GlycolysisCell biologyInflammationImmunologyBiologyMicrobiologyChemistryBiochemistryMetabolismNeutrophil, Myeloperoxidase and Oxidative MechanismsT-cell and B-cell ImmunologyAtherosclerosis and Cardiovascular Diseases