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Brain organoids-on-chip for neural diseases modeling: History, challenges and trends

Hongyong Zhang, Nan Huang, Sumin Bian, Mohamad Sawan

2025Journal of Pharmaceutical Analysis16 citationsDOIOpen Access PDF

Abstract

platform for disease modeling. In this review, we summarize the historical developments, recent advancements, limitations, and future prospects of brain organoid-on-chip technology, aiming to illuminate the transformative potential of this platform in advancing our understanding and treatment of neural diseases.

Topics & Concepts

ChemistryOrganoidComputational biologyNeuroscienceNanotechnologyPsychologyMaterials scienceBiology3D Printing in Biomedical ResearchNeuroscience and Neural EngineeringPluripotent Stem Cells Research
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