Switching to a ‘turn-on’ fluorescent probe for rapid detection of hydrazine in human breast cancer cells using a test-strip
Anirban Karak, Moumi Mandal, Satyajit Halder, Shilpita Banerjee, Dipanjan Banik, Anwesha Maiti, Kuladip Jana, Ajit Kumar Mahapatra
Abstract
Assimilation of styryl bridge has produced a molecular probe TPSBT, capable of hydrazine detection. The appreciable enhancement in fluorescence and its low detection limit helps the probe to detect hydrazine in human breast cancer cell MDA-MB 231.
Topics & Concepts
Detection limitFluorescenceHydrazine (antidepressant)Human breastSKBR3Cancer detectionBreast cancerChemistryTurn (biochemistry)NanotechnologyCancerBiophysicsChromatographyMaterials scienceBiochemistryBiologyMedicineInternal medicineOpticsPhysicsLuminescence and Fluorescent MaterialsMolecular Sensors and Ion DetectionAdvanced biosensing and bioanalysis techniques