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Novel microbial modifications of bile acids and their functional implications

Dan Zheng, Huiheng Zhang, Xiaojiao Zheng, Aihua Zhao, Wei Jia

2024iMeta30 citationsDOIOpen Access PDF

Abstract

This review outlines the recent discoveries of bile acids that have undergone novel microbial modifications, highlighting their biological roles and the profound implications for the development of innovative therapeutic strategies. The review aims to provide valuable insights and breakthroughs for future drug candidates in the expanding field of bile acid therapeutics.

Topics & Concepts

ChemistryComputational biologyBiologyEnvironmental chemistryBiochemistryDrug Transport and Resistance MechanismsPediatric Hepatobiliary Diseases and TreatmentsMetabolism and Genetic Disorders