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Ultra Sensitive Label-Free Detection of Biomolecules Using Vertically Extended Drain Double Gate <i>Si</i>₀.₅<i>Ge</i>₀.₅ Source Tunnel FET

Kumari Nibha Priyadarshani, Sangeeta Singh

2021IEEE Transactions on NanoBioscience33 citationsDOI

Abstract

This work reports a vertically extended drain double gate <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Si</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.5</sub> <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Ge</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.5</sub> source tunnel FET for the biomolecules detection using its electrical properties modulation in presence of biomolecules like cell, DNA, protein, etc. The reported biosensor has a dual source of <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Si</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.5</sub> <italic xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">Ge</i> <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">0.5</sub> and two cavities above each source-channel interface for the immobilization of biomolecules. This immobilization modulates the screening/tunneling length and energy range available for tunneling due to the dielectric constant and charge density variations of the biomolecules. The dual cavity structure increases the control of biomolecules on the source to channel tunneling probability and thus realizes an increased control on electrical performance parameters of the biosensor enabling it to have a higher sensitivity towards the biomolecules. Further, the cavity length of the reported biosensor is kept as 45 nm making it suitable for large sized biomolecules and polymers detection also. Our study demonstrates that the reported biosensor structure is resilient towards the process variations and temperature effects. Moreover, the effect of dielectric modulation and charge density modulation has also been analyzed in terms of the variation in the drive current, ON state current, threshold voltage, transconductance, and sub-threshold slope (SS). The sensitivity of the reported biosensor is also compared with the existing biosensors and it is found to be highly sensitive.

Topics & Concepts

BiosensorBiomoleculeTransconductanceQuantum tunnellingDielectricMaterials scienceOptoelectronicsThreshold voltageNanotechnologyVoltageElectrical engineeringTransistorEngineeringAdvancements in Semiconductor Devices and Circuit DesignSemiconductor materials and devicesNanowire Synthesis and Applications
Ultra Sensitive Label-Free Detection of Biomolecules Using Vertically Extended Drain Double Gate <i>Si</i>₀.₅<i>Ge</i>₀.₅ Source Tunnel FET | Litcius