Transcriptional activation of antioxidant gene expression by Nrf2 protects against mitochondrial dysfunction and neuronal death associated with acute and chronic neurodegeneration
Molly J. Goodfellow, Apurva Borcar, Julie L. Proctor, Tiffany Greco, Robert E. Rosenthal, Gary Fiskum
Topics & Concepts
Oxidative stressMitochondrionNeurodegenerationProgrammed cell deathCell biologyReactive oxygen speciesBiologyMitochondrial ROSSuperoxide dismutaseBiochemistryApoptosisMedicineDiseasePathologyGenomics, phytochemicals, and oxidative stressMitochondrial Function and PathologyTryptophan and brain disorders