Nanotechnology for encapsulation of bioactive components: a review
Meenatai G. Kamble, Anurag Kumar Singh, Sukh Veer Singh, Manisha G. Kamble, Narashans Alok Sagar, Nitu Rani
Abstract
Most of the bioactive compounds are hydrophobic, ineffectively dissolvable, and unstable in harsh storage conditions. Such limitations decrease the stability and bioaccessibility of these compounds as principal challenges for their utilization in the food industries. Nanoencapsulation is one of the most favorable technologies that inhibit the degradation of bioactive compounds from the various phases of food processing, intestinal digestion, and absorption. It empowers the retention of bioactive compounds and their discharge in a well-ordered way, which improves the bio-distribution of bioactive compounds at the target site of the organ. Nanotechnology improves a few characteristics, such as solubility, stability (prevent interaction of encapsulated material with matrix), and bioavailability of bioactive compounds. This review summarized the different carriers for the conveyance of bioactive compounds and their preparation methods. The different nanocarriers for bioactive compounds are association colloids, nanoemulsions, nano-liposomes, solid-lipid nanoparticles, nanostructured lipid carriers, bio-polymeric nanoparticles, and nanofiber. The high and low-energy approaches, electrospinning, and electro-spraying technology are used to prepare nanocarriers. The potential application of nanotechnology has also been discussed in delivering bioactive compounds. Apart from this, the characterization of nanoparticles for human safety and the bioavailability of bioactive compounds after consumption has been discussed.