Theaflavin suppresses necroptosis by attenuating RIPK1-RIPK3-MLKL signaling and mitigates cisplatin-induced kidney injury in mice
Zhi-ya Zhou, Nuo Sun, Ling-han Duan, On-kei Chan, Yaping Li, Yan Liang, Haiyan Yang, Hua-yu Ke, Dong‐Yun Ouyang, Zijian Shi, Qing-bing Zha, Xian‐Hui He
Topics & Concepts
NecroptosisRIPK1Cancer researchPharmacologyAcute kidney injuryChemistryCisplatinCell biologyProgrammed cell deathMedicineApoptosisInternal medicineBiologyBiochemistryChemotherapyCell death mechanisms and regulationChemotherapy-induced organ toxicity mitigationHeavy Metal Exposure and Toxicity