CD8+ T cells specific for an immunodominant SARS-CoV-2 nucleocapsid epitope cross-react with selective seasonal coronaviruses
Katie E. Lineburg, Emma J. Grant, Srividhya Swaminathan, Demetra S.M. Chatzileontiadou, Christopher Szeto, Hannah Sloane, Archana Panikkar, Jyothy Raju, Pauline Crooks, Sweera Rehan, Andrea Nguyen, Lea Lekieffre, Michelle A. Neller, Zhen Tong, Dhilshan Jayasinghe, Keng Yih Chew, Christian A. Lobos, Hanim Halim, Jacqueline M. Burrows, Alan Riboldi‐Tunnicliffe, Weisan Chen, Lloyd D’Orsogna, Rajiv Khanna, Kirsty R. Short, Corey Smith, Stéphanie Gras
Topics & Concepts
EpitopeBiologyVirologyCoronavirusCross-reactivityImmunodominanceT cellT-cell receptorImmune systemImmunityAntigenBetacoronavirusImmunologyCoronavirus disease 2019 (COVID-19)DiseaseInfectious disease (medical specialty)MedicineCross reactionsPathologySARS-CoV-2 and COVID-19 Researchvaccines and immunoinformatics approachesImmunotherapy and Immune Responses