Synthesis of neocryptolepines and carbocycle-fused quinolines and evaluation of their anticancer and antiplasmodial activities
Bhornrawin Akkachairin, Warabhorn Rodphon, Onrapak Reamtong, Mathirut Mungthin, Jumreang Tummatorn, Charnsak Thongsornkleeb, Somsak Ruchirawat
Topics & Concepts
ChemistryQuinolineDoxorubicinCytotoxicityStereochemistryCancer cell linesCombinatorial chemistryAnticancer drugSelectivityCell cultureRing (chemistry)CisplatinAntimalarial AgentCancer cellPlasmodium falciparumDrugCancerPharmacologyIn vitroBiochemistryOrganic chemistryChemotherapyMalariaMedicineBiologyGeneticsImmunologyCatalysisInternal medicineSurgerySynthesis and bioactivity of alkaloidsCancer therapeutics and mechanismsSynthesis and pharmacology of benzodiazepine derivatives