Synthesis and properties of 1-[(3-fluoroadamantan-1-yl)methyl]-3-R-ureas and 1,1′-(alkan-1,n-diyl)bis{3-[(3-fluoroadamantan-1-yl)methyl]ureas} as promising soluble epoxide hydrolase inhibitors
Д. В. Данилов, V. S. D’yachenko, В. В. Бурмистров, Г. М. Бутов, И. А. Новаков
Topics & Concepts
ChemistryIsocyanateAdamantaneReagentAcetic acidEpoxideOrganic chemistryFluorineMedicinal chemistryPolyurethaneCatalysisEicosanoids and Hypertension PharmacologyNitric Oxide and Endothelin EffectsHormonal Regulation and Hypertension