Protocadherin 20 promotes ferroptosis by suppressing the expression of Sirtuin 1 and promoting the acetylation of nuclear factor erythroid 2-related factor 2 in hepatocellular carcinoma
LV Jun, Wang Chen, Liang Han, Liu Yanmin, Zeng Qinglei, Zhu Pengfei
Topics & Concepts
Downregulation and upregulationGene knockdownViability assayGPX4Cancer researchSirtuin 1ChemistryCell biologyGlutathioneBiologyOxidative stressCellApoptosisBiochemistryGlutathione peroxidaseSuperoxide dismutaseEnzymeGeneFerroptosis and cancer prognosisCancer-related molecular mechanisms researchRNA modifications and cancer