Synthesis, biological evaluation and molecular docking studies of novel 1,2,3-triazole tethered chalcone hybrids as potential anticancer agents
Nirmala Gurrapu, E. Praveen Kumar, Prashanth Kumar Kolluri, Shravani Putta, Sree Kanth Sivan, N. J. P. Subhashini
Topics & Concepts
ChemistryChalconeHeLaADMECytotoxicityMTT assayIn vitroCytotoxic T cellDocking (animal)In silicoMCF-7IC50Cancer cellStereochemistryTriazoleCisplatinBiochemistryCancerHuman breastOrganic chemistrySurgeryNursingInternal medicineMedicineChemotherapyGeneSynthesis and biological activityClick Chemistry and ApplicationsSynthesis and Biological Evaluation