Litcius/Paper detail

In vivo chimeric antigen receptor (CAR)-T cell therapy

Adrian Bot, Andrew M. Scharenberg, Kevin M. Friedman, Lin T. Guey, Robert Hofmeister, James I. Andorko, Michael Klichinsky, Frank Neumann, Jagesh V. Shah, Andrew J. Swayer, Kyle Trudeau, Drew Weissman, Matthias T. Stephan, Christian J. Buchholz, Carl H. June

2025Nature Reviews Drug Discovery65 citationsDOI

Topics & Concepts

Ex vivoChimeric antigen receptorIn vivoCellGenetic enhancementCell therapyCancer researchMedicineViral vectorAntigenClinical trialImmunotherapyImmunologyT cellComputational biologyReceptorVector (molecular biology)RNAChemistryBiologyCAR-T cell therapy researchBiomedical and Engineering EducationBiomedical Ethics and Regulation