CRISPR/Cas12a-drived fluorescent and electrochemical signal-off/on dual-mode biosensors for ultrasensitive detection of EGFR 19del mutation
Shiying Zhou, Jiangbo Dong, Liyuan Deng, Zhen Huang, Peng Lu, Guixue Wang, Mei Yang, Danqun Huo, Changjun Hou
Topics & Concepts
BiosensorCRISPRDetection limitChemistryFluorescenceRolling circle replicationCombinatorial chemistryMolecular biologyBiologyDNABiochemistryGenePhysicsChromatographyDNA replicationQuantum mechanicsCRISPR and Genetic EngineeringAdvanced biosensing and bioanalysis techniquesRNA and protein synthesis mechanisms