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Powerful and robust inference of complex phenotypes' causal genes with dependent expression quantitative loci by a median-based Mendelian randomization

Lin Jiang, Lin Miao, Guorong Yi, Xiangyi Li, Chao Xue, Mulin Jun Li, Hailiang Huang, Miaoxin Li

2022The American Journal of Human Genetics21 citationsDOIOpen Access PDF

Topics & Concepts

Mendelian randomizationGenome-wide association studyPleiotropyLinkage disequilibriumGenetic associationExpression quantitative trait lociCausal inferenceBiologyComputational biologyGeneticsInferenceGenePhenotypeComputer scienceAlleleSingle-nucleotide polymorphismStatisticsArtificial intelligenceMathematicsGenetic variantsHaplotypeGenotypeGenetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock
Powerful and robust inference of complex phenotypes' causal genes with dependent expression quantitative loci by a median-based Mendelian randomization | Litcius