Single-cell transcriptome dissection of the toxic impact of Di (2-ethylhexyl) phthalate on primordial follicle assembly
Junjie Wang, Yu Tian, Minghao Li, Yanqin Feng, Li Kong, Fa‐Li Zhang, Wei Shen
Abstract
These findings offer substantial novel insights into the reproductive toxicity of DEHP exposure during murine germ cell cyst breakdown and primordial follicle formation. These results may enhance the understanding of DEHP exposure on reproductive health.
Topics & Concepts
PhthalateBiologyTranscriptomeGerm cellAndrologyOvarian follicleFolliculogenesisFollicleCell biologyGene expressionInternal medicineEndocrinologyEmbryoOvaryGeneChemistryEmbryogenesisGeneticsMedicineOrganic chemistryEffects and risks of endocrine disrupting chemicalsPluripotent Stem Cells ResearchBiomedical Ethics and Regulation