Concurrent inhibition of CDK2 adds to the anti-tumour activity of CDK4/6 inhibition in GIST
Inga‐Marie Schaefer, Matthew L. Hemming, Meijun Z. Lundberg, Matthew Serrata, Isabel Goldaracena, Ninning Liu, Peng Yin, João A. Paulo, Steven P. Gygi, Suzanne George, Jeffrey A. Morgan, Monica M. Bertagnolli, Ewa Sicińska, Chen Chu, Shanshan Zheng, Adrián Mariño‐Enríquez, Jason L. Hornick, Chandrajit P. Raut, Wen‐Bin Ou, George D. Demetri, Sinem K. Saka, Jonathan A. Fletcher
Topics & Concepts
GiSTCancer researchCyclin-dependent kinaseCyclin D1Cyclin-dependent kinase 2Cell cycleBiologyCell growthImatinibCDK inhibitorCellStromal cellBiochemistryMyeloid leukemiaGastrointestinal Tumor Research and TreatmentAdvanced Breast Cancer TherapiesHER2/EGFR in Cancer Research