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Blockade of IL-7 signaling suppresses inflammatory responses and reverses alopecia areata in C3H/HeJ mice

Zhenpeng Dai, Eddy Hsi Chun Wang, Lynn Petukhova, Yuqian Chang, Eunice Yoojin Lee, Angela M. Christiano

2021Science Advances40 citationsDOIOpen Access PDF

Abstract

-tropic cytokines enhanced therapeutic effects in the treatment of AA, and invite further clinical investigation.

Topics & Concepts

Alopecia areataBlockadeImmunologyMedicineInflammationBlocking (statistics)Signal transductionHair growthReceptorBiologyInternal medicineCell biologyPhysiologyMathematicsStatisticsHair Growth and DisordersDermatology and Skin DiseasesImmune Cell Function and Interaction
Blockade of IL-7 signaling suppresses inflammatory responses and reverses alopecia areata in C3H/HeJ mice | Litcius