Paclitaxel and Lapatinib dual loaded chitosan-coated PLGA nanoparticles enhance cytotoxicity by circumventing MDR1-mediated trastuzumab resistance in HER2 positive breast cancers: In-vitro and in-vivo studies
Subrahmanyam Pitchika, Suvendu Kumar Sahoo
Topics & Concepts
PaclitaxelTrastuzumabIn vivoLapatinibPharmacologyCytotoxicityChitosanMultiple drug resistanceChemistryIn vitroCancer cellPLGADoxorubicinBreast cancerMedicineChemotherapyCancerInternal medicineBiochemistryBiologyAntibioticsBiotechnologyNanoparticle-Based Drug DeliveryAdvanced Drug Delivery SystemsRNA Interference and Gene Delivery