Advances in active targeting of ligand-directed polymeric nanomicelles <i>via</i> exploiting overexpressed cellular receptors for precise nanomedicine

Abstract

receptor-mediated endocytosis through exploiting receptors robustly expressed on the exterior of the intended tissue while minimizing their toxic effects. In this review, the up-to-date approaches of harnessing active targeting ligands to exploit certain overexpressed receptors will be summarized concerning the functionalization of the exterior of PMs for ameliorating their targeting potential in the scope of nanomedicine.

Topics & Concepts