Litcius/Paper detail

The antioxidant peptides from walnut protein hydrolysates and their protective activity against alcoholic injury

Peihang Chen, Pantian Huang, Yingyan Liang, Qiaoe Wang, Jianyin Miao

2024Food & Function29 citationsDOI

Abstract

). In the ethanol injury model, three antioxidant peptides enhanced the survival of cells treated with ethanol from 47.36% to 62.69%, 57.06% and 71.64%, respectively. Molecular docking results showed that the three antioxidant peptides could effectively bind to Keap1, CYP2E1 and TLR4 proteins. These results suggested that walnut-derived antioxidant peptides could be potential antioxidants and hepatoprotective agents for application in functional foods.

Topics & Concepts

AntioxidantChemistryHydrolysateEthanolFood scienceGlutathioneBiochemistryEC50HydrolysisEnzymeIn vitroProtein Hydrolysis and Bioactive PeptidesBiochemical effects in animalsMuscle metabolism and nutrition