The antioxidant peptides from walnut protein hydrolysates and their protective activity against alcoholic injury
Peihang Chen, Pantian Huang, Yingyan Liang, Qiaoe Wang, Jianyin Miao
Abstract
). In the ethanol injury model, three antioxidant peptides enhanced the survival of cells treated with ethanol from 47.36% to 62.69%, 57.06% and 71.64%, respectively. Molecular docking results showed that the three antioxidant peptides could effectively bind to Keap1, CYP2E1 and TLR4 proteins. These results suggested that walnut-derived antioxidant peptides could be potential antioxidants and hepatoprotective agents for application in functional foods.
Topics & Concepts
AntioxidantChemistryHydrolysateEthanolFood scienceGlutathioneBiochemistryEC50HydrolysisEnzymeIn vitroProtein Hydrolysis and Bioactive PeptidesBiochemical effects in animalsMuscle metabolism and nutrition