Self-Assembling Peptide Dendron Nanoparticles with High Stability and a Multimodal Antimicrobial Mechanism of Action
Zhenheng Lai, Jian Qiao, Guoyu Li, Changxuan Shao, Yongjie Zhu, Xiaojie Yuan, Hongyu Chen, Anshan Shan
Abstract
therapeutic efficacy without apparent resistance development. These advancements may facilitate the development of peptide-based antibiotics in clinical settings.
Topics & Concepts
PeptideDendrimerNanomedicineBiophysicsNanobiotechnologyMaterials scienceIn vivoAntimicrobial peptidesNanoparticleChemistryNanotechnologyBiochemistryBiologyBiotechnologyAntimicrobial Peptides and ActivitiesPeptidase Inhibition and AnalysisRNA Interference and Gene Delivery