Delivery Mode Affects Stability of Early Infant Gut Microbiota
Caroline M. Mitchell, Chiara Mazzoni, Larson Hogstrom, Allison Bryant, Agnès Bergerat, Avital Cher, Shawna Pochan, Penelope Herman, Maureen H. Carrigan, Karen Sharp, Curtis Huttenhower, Eric S. Lander, Hera Vlamakis, Ramnik J. Xavier, Moran Yassour
Abstract
(primarily according to 16S sequencing), despite their difference in exposure to the birth canal. Finally, a comparison of microbial strain profiles between infants and maternal vaginal or rectal samples finds evidence for mother-to-child transmission of rectal rather than vaginal strains. These results suggest differences in colonization stability as an important factor in infant gut microbiome composition rather than birth canal exposure.
Topics & Concepts
BacteroidesMicrobiomeVaginal deliveryBiologyGut microbiomeGut floraPhysiologyPregnancyObstetricsMedicineImmunologyBacteriaBioinformaticsGeneticsGut microbiota and healthUrinary Tract Infections ManagementPelvic floor disorders treatments